DSS - Dispersion shrinkage for sequencing data
DSS is an R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.
Last updated 5 months ago
sequencingrnaseqdnamethylationgeneexpressiondifferentialexpressiondifferentialmethylation
7.30 score 80 dependencies 5 dependentsPROPER - PROspective Power Evaluation for RNAseq
This package provide simulation based methods for evaluating the statistical power in differential expression analysis from RNA-seq data.
Last updated 5 months ago
immunooncologysequencingrnaseqdifferentialexpression
5.06 score 5 dependencies 1 dependents