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DSS - Dispersion shrinkage for sequencing data
DSS is an R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.
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sequencingrnaseqdnamethylationgeneexpressiondifferentialexpressiondifferentialmethylation
5.77 score 4 dependents 7 scripts 1.6k downloadsPROPER - PROspective Power Evaluation for RNAseq
This package provide simulation based methods for evaluating the statistical power in differential expression analysis from RNA-seq data.
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immunooncologysequencingrnaseqdifferentialexpression
5.35 score 1 dependents 37 scripts 575 downloads